Targeted Therapies in PsA
Tailored treatment options for patients with psoriatic arthritis and psoriasis: review of established and new biologic and small molecule therapies The diverse clinical picture of PsA suggests the need to…
The 9 Muses are daughters of Zeus and Mnemosyne, Greek goddesses personifying the inspiration for the sciences and the arts.
My highly opinionated news-blog draws inspiration from both the science and the art of Rheumatology.
Monitoring PsA
Higher C-Reactive Protein Levels Signal Need for Early Intervention in Patients with Psoriatic Arthritis An observational study of psoriatic arthritis patients indicated that initial levels of C-reactive protein are…hcplive.com|By Andrew…
Detecting PsA Early
Bone remodeling in psoriasis and psoriatic arthritis: an update Curr Opin Rheumatol. 2016 Jan;28(1):66-75. doi: 10.1097/BOR.0000000000000232. Review ncbi.nlm.nih.gov|By Paine A and Ritchlin C It appears that the enthesis is where…
From Psoriasis To Arthritis
Clinical Risk Factors for the Development of Psoriatic Arthritis Among Patients with Psoriasis: A Review of Available Evidence Psoriatic arthritis (PsA), a chronic inflammatory arthritis, affects about 10 % of patients…
The Psoriatic Plague
Fewer Psoriasis Patients Satisfied with Current Treatments Science Daily reports the results of a new survey by Health Union that assessed nearly 600 individuals with plaques psoriasis. They found that…
PsO/PsA & Th22/Th9
Th22 Cells Contribution in Immunopathogenesis of Rheumatic Diseases Newly identified T helper cell 22 (Th22) is a subset of CD4+T cells with specific properties apart from other known CD4+ T…
T-helper 22 (Th22)
Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodelling 1Molecular Immunology, Department of Allergy and Clinical Immunology, National Heart and Lung… jci.org Th22 cells…
T-helper 9 (Th9)
IL-9 and Th9 cells: progress and challenges T[h] 9 cells are a new subset of helper T cells, and the signature cytokine for T[h] 9 cells is IL-9. Both T[h]…
Autoimmune Heterogeneity
Heterogeneity of autoimmune diseases: pathophysiologic insights from genetics and implications for new therapies Recent advances in genetics have deepened our understanding of the pathogenic mechanisms behind autoimmune and immune-mediated diseases.…
Ustekinumab & Th17
IL-12 and IL-23 cytokines: from discovery to targeted therapies for immune-mediated inflammatory diseases Cua and colleagues discuss the cellular and molecular rationale for targeting IL-12 and IL-23 for therapeutic purposes…
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