Risks of Gout


Gout associated with elevated risk for kidney stones

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Patients with gout are more likely to develop nephrolithiasis than population controls, but the majority of medications used frequently by gout patients do not alter this risk, according to the results…

Hyperuricemia and chronic kidney disease: an enigma yet to be solved

(2014). Hyperuricemia and chronic kidney disease: an enigma yet to be solved. Renal Failure: Vol. 36, No. 9, pp. 1351-1359.

High uric acid levels linked to dementia risk

Older people with higher levels of serum uric acid may have a greater risk for dementia than those with lower levels, results of a longitudinal study suggest.

Elevated Uric Acid Linked to Dementia in the Elderly

Hyperuricemia tied to vascular or mixed dementia, but…

Uric acid and incident dementia over 12 years of follow-up: a population-based cohort study

Objectives In patients with gout, maintaining too low serum uric acid (SUA) level with urate-lowering therapy is a concern because uric acid is thought to be neuroprotective. However, the relation between SUA and dementia remains debated. This study aimed to investigate the impact of SUA level on th…

Other studies suggest a neuroprotective role for uric acid. Hyperuricaemia, for example, is associated with a lower risk for Alzheimer Disease.

The association with dementia in the current study, however, is with vascular dementia.

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Epidemiological studies suggest that higher serum uric acid (sUA) level is significantly associated with nonalcoholic fatty liver disease (NAFLD) development. However, little information is available on the relationships between sUA and NAFLD remission. In the present study, 841 NAFLD males (30–75 y…

Not only is hyperuricaemia associated with fatty liver disease, reduction of serum uric acid led to improvement of steatohepatitis. This suggests causality as well as reversibility.