In patients with knee osteoarthritis, there was a high concordance between scanning electron microscopy…
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Take-home-message: we need to improve our ability to sensitively detect and correctly identify synovial fluid crystals.


A synovial fluid wet smear stained with Alizarin red S. The darker red deposits have the appearance of hydroxyapatitc accumulations. The specimen is from a patient with end-stage renal disease (magnification × 720, original magnification × 200). Reproduced with permission from ref. 94. (Copyright 1992, Ciba-Geigy Corp.)
Alexander Yavorskyy a, Aaron Hernandez-Santana a, Geraldine McCarthy b and Gillian McMahon *aaBioanalytical Chemistry & Diagnostics Group, National Centre for Sensor Research, School of Chemical Sciences, Dublin City University, Dublin 9, Ireland. E-mail: Gillian.McMahon@dcu.ie; Tel: +353 1 7005914…
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