Identifying Preclinical Psoriatic Arthritis in Hope of Prevention
“A variety of musculoskeletal symptoms preceded an identification of PsA by approximately 6 years. The strongest predictors at baseline for the future development of PsA were heel pain, high fatigue, and high stiffness—in particular, back stiffness. Furthermore, arthralgia of any kind was a significant predictor for future PsA in women but not men.”
Comorbidities in psoriatic arthritis flag worse prognosis
“The presence of comorbidities in psoriatic arthritis (PsA) patients on initial tumor necrosis factor inhibitor (TNFi) treatment “was associated with higher disease activity, shorter adherence to the first TNFi, and reduced clinical response.”
Periarticular Symptoms Worsen PsA
“Patients with psoriatic arthritis (PsA) who have the periarticular manifestations of enthesitis and dactylitis have a higher disease burden than those without these features.”