Predicting Bad PsA

Identifying Preclinical Psoriatic Arthritis in Hope of Prevention

Dr Kevin Deane explains how this new research may provide a window of opportunity for preventing psoriatic arthritis.

“A variety of musculoskeletal symptoms preceded an identification of PsA by approximately 6 years. The strongest predictors at baseline for the future development of PsA were heel pain, high fatigue, and high stiffness—in particular, back stiffness. Furthermore, arthralgia of any kind was a significant predictor for future PsA in women but not men.”

Comorbidities in psoriatic arthritis flag worse prognosis

MADRID – Focus on comorbidities to improve treatment.

“The presence of comorbidities in psoriatic arthritis (PsA) patients on initial tumor necrosis factor inhibitor (TNFi) treatment “was associated with higher disease activity, shorter adherence to the first TNFi, and reduced clinical response.”

Periarticular Symptoms Worsen PsA

Disease burden higher when enthesitis and dactylitis are present

“Patients with psoriatic arthritis (PsA) who have the periarticular manifestations of enthesitis and dactylitis have a higher disease burden than those without these features.”