Osteoporosis: Calcium & Vitamin D

CHICAGO — December 27, 2017 — Supplements containing calcium, vitamin D, or both, did not…

Update on Vitamin D and Calcium Supplements for Reducing Fracture Risk

The USPSTF commissioned a systematic evidence review on vitamin D, calcium, and combined supplementation for the primary prevention of…

A review of most observational studies in “free range” healthy elderly without osteoporosis or increased fracture risks did not demonstrate any benefit from Calcium and Vitamin D supplementation in preventing fractures.

Middle-age healthy patients receiving monthly high-dose bolus colecalciferol did not have a reduced risk for fracture or falls.

It appears from this randomised prospective trial, rendering the elderly population replete with Vitamin D DID NOT reduce fall propensity nor reduce non-vertebral fracture rates.

Another good idea bites the dust.

Among older adults, a lower 24,25-dihydroxyvitamin D to 25-hydroxyvitamin D ratio, also known as the…

24,25-dihydroxyvitamin D is an inactive metabolite of 25-hydroxyvitamin D (D3), destined for excretion.  What the body needs will be converted from D3 to active 1,25-dihydroxyvitamin D.  The higher the ratio of 24,25-dihydroxyvitamin D to D3, therefore, reflects the adequacy of Vitamin D for calcium homeostasis and bone growth.  Understandably, a higher ratio correlated better with bone mass density and a lower hip fracture risk in this study.