Microbiome & RA

Distal Airway Dysbiosis Present in Early RA

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Distal airway dysbiosis is present in untreated early rheumatoid arthritis (RA) and similar to that detected in sarcoidosis lung inflammation, according to a recent study. This community perturbation, which correlates with local and systemic autoimmune/inflammatory changes, may potentially drive ini…

Bacteria that cause gum disease may also cause rheumatoid arthritis

A type of bacteria found in severe gum disease may trigger many cases of…
nbcnews.com|By Maggie Fox

Searching for Rheumatoid Arthritis in the Gut

Rheumatology, rheumatoid arthritis, ra, microbiota, biomarkers, immune disorders, arthritis, rheumatoid arthritis diagnosis, mayo clinic, gut bacteria, bacteria, internal medicine, gut
A pair of recent studies look in an interesting place to find commonality among rheumatoid arthritis sufferers: their guts.
hcplive.com|By Ryan Black

Evidence of Gut Microbe Found in RA Patients

Subgroups of rheumatoid arthritis (RA) patients have differential IgG or IgA immune reactivity with Prevotella copri, an intestinal microbe, which appears to be specific for this disease, according to a recent study. These observations provide evidence that P. copri is immune-relevant in RA pathogen…

How Rheumatoid Arthritis Can Result from Provocation of the Immune System by Microorganisms and Viruses

The pathogenesis of rheumatoid arthritis (RA),…

IgA ACPA and Plasmablasts Point to Microbiome in Pre-Clinical Rheumatoid

Serum antibodies precede the development of clinical rheumatoid arthritis (RAby) by many years, and yet we still have much to learn about this preclinical phase. Of particular interest has been the observation that IgA anti-CCP antibodies are commonly encountered in patients with RA raising question…

Gut Microbiome Shapes Risk and Response in Rheumatoid Arthritis

In Genome Medicine, Mayo Clinic researchers investigated a cohort of rheumatoid arthritis (RA) patients, their relatives and a healthy control group analyzing the gut microbiome vial16S ribosomal DNA analysis of fecal samples. They showed that RA had decreased gut microbial diversity which correlate…

Could Some Infections Protect Against Rheumatoid Arthritis?

Scientists have long suspected that certain bacterial infections may trigger RA.
Infections of the gastrointestinal and urogenital tracts appear to reduce RA risk, but prostate and respiratory infections do not.