IgG Subclasses

IgG Subclasses and Allotypes: From Structure to Effector Functions

Of the five immunoglobulin isotypes, Immunoglobulin G (IgG) is most abundant in human serum. The four subclasses, IgG1, IgG2, IgG3 and IgG4 which are highly conserved, differ in their constant region,…

Immunoglobulin G Deficiency Clinical Presentation: History, Physical, Causes

Immunodeficiency diseases are commonly classified into disorders that affect one or more of the 4 major…

IgG Subclass Deficiency

The main immunoglobulin (Ig) in human blood is IgG.…


Serum IgG Subclasses in Autoimmune Diseases

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To characterize serum IgG subclass levels in several autoimmune diseases, including primary Sjogren syndrome (pSS), systemic sclerosis (SSc), systemic lupus erythematosus (SLE), and primary biliary cirrhosis (PBC). We aimed to analyze…