Metformin Mechanism
Metformin is a biguanide widely used for the therapy of type 2 diabetes mellitus. It has been shown that this compound ameliorates hyperglycemia without promoting insulin secretion, causing weight gain or generating hypoglycemia.…
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Cellular and molecular mechanisms of metformin: an overview
Considerable efforts have been made since the 1950s to better understand the cellular and molecular mechanisms of action of metformin, a potent…
clinsci.org
Molecular mechanism of action of metformin: old or new insights?
Metformin is the first-line drug treatment for type 2 diabetes. Globally, over 100 million patients are…
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Effects of metformin on the gut microbiome
The effects of metformin on the gut microbiome is stimulation of the beneficial gut bacterium, Akkermansia, which prevents a leaky gut and inflammation.
askdrray.com
Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug
nature.com
Effect of Metformin on Metabolic Improvement and Gut Microbiota
Metformin is commonly used as the first line of medication for the treatment of metabolic syndromes, such as obesity and type 2 diabetes (T2D). Recently, metformin-induced changes in the gut microbiota have been reported; however, the relationship between metformin treatment and the gut microbiota r…
aem.asm.org
The mechanisms of action of metformin
Metformin is a widely-used drug that results in clear benefits in relation to glucose metabolism and…
link.springer.com