Helminth Therapy

<i>BMC Immunology</i> is an open access journal publishing original peer-reviewed research articles in molecular, cellular, tissue-level, organismal, functional, and developmental aspects of the immune system.

Background/Purpose: Treatment with helminthes…

Instead of eating worms to try to treat autoimmune and allergic diseases, scientists try to isolate the compound(s) secreted by worms, which can damping the immune response (allowing the parasite to survive) without obliterating it (otherwise killing the host).


In the days before the advent of antibiotics, Syphilis can sometimes be cured by malaria: the spiking fevers help to kill the spirochaetes.
Lupus is apparently rare in areas where malaria is endemic.
The authors believe that, one of the chemicals responsible for rendering the immune system tolerogenic to worms, can help in Lupus Nephritis. If so, the days of massive immunosuppression needed to control autoimmune diseases may be behind us.