For acute gout, corticosteroids look safer than NSAIDs
A meta-analysis of six randomized, controlled trials suggests equal efficacy, but patients taking corticosteroids had a lower frequency of indigestion, nausea, and vomiting and a higher frequency of rash.
mdedge.com
Allopurinol dose escalation to achieve serum urate below 6 mg/dL: an open-label extension study
Objectives To determine the long-term safety and efficacy of allopurinol dose escalation (DE) to…
ard.bmj.com
The Differences in the Mechanisms of Action Between Allopurinol and Febuxostat
Evidence-Based Medicine Consult
ebmconsult.com
Lesinurad Plus Febuxostat Effective for Tophaceous Gout
When lesinurad 400mg was added to febuxostat, significantly more patients achieved target sUA by Month 6 (76.1%; P<0.0001) vs. febuxostat alone (46.8%);…
clinicalpainadvisor.com
FDA Approves Duzallo for Hyperuricemia Associated With Uncontrolled Gout
The US FDA has approved a new fixed-dose and dual-mechanism treatment option for uncontrolled gout.
rheumatologyadvisor.com
