Dysbiosis & SpA

Fecal Metabolomics Implicate Tryptophan Pathway in Pediatric Spondyloarthritis

Using metabolomic profiling of fecal samples of children with enthesitis-related arthritis (ERA), researchers found that children with ERA may have lower levels of…

Microbiota-activated PPAR-γ signaling inhibits dysbiotic Enterobacteriaceae expansion

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Normally, the lumen of the colon lacks oxygen. Fastidiously anaerobic butyrate-producing…

A longitudinal study of fecal calprotectin and the development of inflammatory bowel disease in ankylosing spondylitis

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Patients with ankylosing spondylitis (AS) are at increased risk of developing inflammatory bowel disease (IBD). We aimed to determine the variation in fecal calprotectin in AS over 5 years in relation to disease activity and medication and also …