Dysbiosis & Crohn's/SpA

Crohn’s Arthritis Linked to E. Coli Infection

Articular manifestations of Crohn’s disease affects a significant number of patients with either…

Research uncovers bacteria linking Crohn’s disease to arthritis

Research Uncovers Bacteria Linking Crohn’s Disease to Arthritis

Patients with Crohn’s disease, a type of inflammatory bowel disease (IBD) that causes abdominal pain and diarrhea, can also experience joint pain. In Crohn’s disease, which affects about 800,000 Americans, the immune system can attack not only the bowels, but the musculoskeletal system as well, lead…

Spondyloarthropathies: E. coli links IBD to spondyloarthritis


Predicting Crohn’s Disease in Those with Ankylosing Spondylitis

A recent study found a strong association between increased levels of an inflammatory…

A longitudinal study of fecal calprotectin and the development of inflammatory bowel disease in ankylosing spondylitis

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Patients with ankylosing spondylitis (AS) are at increased risk of developing inflammatory bowel disease (IBD). We aimed to determine the variation in fecal calprotectin in AS over 5 years in relation to disease activity and medication and also to study the incidence of and predictors for developmen…

Dysbiosis and zonulin upregulation alter gut epithelial and vascular barriers in patients with ankylosing spondylitis

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Background Dysbiosis has been recently demonstrated in patients with ankylosing spondylitis (AS) but its implications in the modulation of intestinal immune responses have never been studied. The aim of this study was to investigate the role of ileal bacteria in modulating local and systemic immune…