Checkpoint Inhibitors & Autoimmunity

Checkpoint Inhibitors Causing Rheumatic Disease

Calabrese and Velcheti have reviewed the current understanding that underlies a new drug-induced rheumatic disease – checkpoint inhibitor arthritis and…

Rheumatic and Musculoskeletal Immune-Related Adverse Events Due to Immune Checkpoint Inhibitors: A Systematic Review of the Literature

LC Cappelli et al. Arthritis Care Res (Hoboken) None

Managing Inflammatory Arthritis From Checkpoint Inhibitors

Inflammatory arthritis is an underappreciated adverse event of immune checkpoint blockade that requires special management considerations.

Successful treatment of arthritis induced by checkpoint inhibitors with tocilizumab: a case series

Background Immune checkpoint inhibitors (ICIs) have significantly improved outcomes for patients with numerous cancers. However, these therapies are associated with immune-related adverse events (irAEs), which are inflammatory side effects potentially affecting any organ. Cases of ICI-induced inflam…