AS: Treatment Failure
Specific Factors Tied to Treatment Nonresponse in AxSpA Age, disease activity, HLA-B27, and type of TNF blocker came in to play medpagetoday.com Interestingly, 4 factors stood out in predicting treatment…
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My highly opinionated news-blog draws inspiration from both the science and the art of Rheumatology.
AS: Drug Withdrawal & Flare
Flare of nonradiographic axial SpA occurs often after adalimumab withdrawal for remission Many patients couldn’t get back into remission when adalimumab was reinstated. mdedge.com Efficacy and Safety of Continuing Versus…
Targeting AS Damage
Bone formation in ankylosing spondylitis during anti-tumour necrosis factor therapy imaged by 18 F-fluoride positron emission tomography academic.oup.com Spondyloarthropathies: TNF inhibitors and structural damage in ankylosing spondylitis <p>Whether TNF inhibitors…
AS Damage: Low-Dose CT
Spondyloarthritis: Low-dose CT for spondyloarthritis — a brilliant new chapter? <p>Outcome assessment of disease modification represents a major challenge to the development of… nature.com Low-Dose CT Scans Detect Bone Proliferation…
Targeting AS Inflammation
Ankylosing Spondylitis Disease Activity Score (ASDAS): 2018 update of the nomenclature for disease activity states The Ankylosing Spondylitis Disease Activity Score… ard.bmj.com Disease activity in ankylosing spondylitis: the global therapeutic…
AS Inflammation: MRI
Sacroiliitis: Causes, symptoms, and treatment Sacroiliitis is a condition where one or both of the sacroiliac joints become inflamed. It is often misdiagnosed as lower back pain. Learn more. medicalnewstoday.com…
Pain in AS
Pain in ankylosing spondylitis: a neuro-immune collaboration <p> <list list-type="bullet"> <li><p>Inflammatory mediators can directly and indirectly induce pain</p></li> <li><p>Pain in ankylosing spondylitis (AS) is not strictly inflammatory and involves a……
Microbiome & SpA
Gut Microbiota Perturbations in Reactive Arthritis and Postinfectious Spondyloarthritis OBJECTIVE Reactive arthritis (ReA) is an inflammatory disorder occurring several weeks after gastrointestinal or genitourinary tract infections. HLA-B27 positivity is considered…
Non-Radiographic Axial Spondyloarthritis
Nonradiographic axial spondyloarthritis: clinical and therapeutic relevance Current classification criteria for axial spondyloarthritis (axSpA) provide for the… arthritis-research.biomedcentral.com
Enteropathic Spondyloarthritis
Impact of Inflammatory Bowel Disease in Early Spondyloarthritis in a Prospective Longitudinal Cohort Background/Purpose: Inflammatory bowel disease… acrabstracts.org MAIT cells: not just another brick in the wall ard.bmj.com IL-7 primes…
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