Anti-Phospholipid Syndrome

Can Infections Trigger Autoimmunity?

Case reports suggest a post-infectious association with antiphospholipid syndrome
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Anti-Phospholipid antibodies are found in about a third of SLE patients, of which a fraction develop the Anti-Phospholipid Syndrome, manifesting as recurrent miscarriages and clotting episodes.
These autoantibodies can also be triggered by certain infections.

Systematic review of case reports of antiphospholipid syndrome following infection

Prevention of Recurrent Thrombosis in Antiphospholipid Syndrome: Different from the General Population?

Antiphospholipid syndrome (APS) is characterized by arterial and/or venous thrombosis with or without pregnancy morbidity in the presence of autoantibodies targeting proteins that associate with membrane phospholipids, termed “antiphospholipid antibodies” (aPL). Management of arterial and venous thr…
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