Interferons & APS

Antiphospholipid Syndrome

Antiphospholipid syndrome (APS) is a disorder that manifests clinically as recurrent venous or arterial…
emedicine.medscape.com

Monocyte type I interferon signature in antiphospholipid syndrome is related to proinflammatory monocyte subsets, hydroxychloroquine and statin use

Several autoimmune diseases, most notably systemic lupus erythematosus (SLE), show an overexpression of type I interferon (IFN)-inducible genes, termed the IFN signature.1 The IFN signature is associated with endothelial progenitor cells (EPC) dysfunction in SLE2 and the recent report by Grenn et al…
ardbeta.bmj.com

Is this how Hydroxychloroquine and statins work to immunomodulate in APS?

Will interferon inhibition emerge as a treatment for APS? CAPS even, perhaps?