The link between gut and joint inflammation in spondyloarthritis (SpA) is well established, in particular in ankylosing spondylitis (AS) and peripheral SpA. In 1995, Mielants et al1 discovered that almost 50% of patients with SpA have subclinical…
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Study links specific invariant T cells to pathogenesis of ankylosing spondylitis
Investigators of this study found mucosal-associated invariant T cells may play a role in the pathogenesis…
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Objective Ankylosing spondylitis (AS) is a chronic inflammatory disease of unknown origin in which interleukin (IL) 17 has been genetically and therapeutically recognised as a key player. Identification of the cellular sources and inducers of IL-17 is crucial in our understanding of the drivers of i…
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