A Brief History of IL-1 and IL-1 Ra in Rheumatology
The history of what, in 1979, was calledinterleukin-1(IL-1), orchestrator of leukocyte inter-communication, began many years before then, initially by the observation of fever induction via the endogenous pyrogen (EP) (1974) and…
journal.frontiersin.org
Interleukin‐9 and T helper type 9 cells in rheumatic diseases
Interleukin (IL)‐9 is a 28‐30 kDa monomeric glycosylated polypeptide belonging to the IL‐7/IL‐9 family of proteins that bind to a composite receptor consisting of the private receptor IL‐9R…
onlinelibrary.wiley.com
Transcription factor NFAT5 promotes macrophage survival in rheumatoid arthritis
1Center for Integrative Rheumatoid Transcriptomics and Dynamics, The Catholic University of Korea,…
jci.org
Innate Lymphoid Cells Play Key Role in Rheumatic Diseases
Balancing between tissue homeostasis and inflammation
medpagetoday.com
Targeting innate immunity to downmodulate adaptive immunity and reverse type 1 diabetes
Targeting innate immunity to downmodulate adaptive immunity and reverse type 1 diabetes…
dovepress.com
Epigenetics of CD4+ T cells in autoimmune diseases
Purpose of review: Autoimmune disorders are a group of overactive symptoms because of…
journals.lww.com
Autoreactive helper T cells alleviate the need for intrinsic TLR signaling in autoreactive B cell activation
3Division of Rheumatology, Department of…
insight.jci.org
B cell OX40L supports T follicular helper cell development and contributes to SLE pathogenesis
Objectives TNFSF4 (encodes OX40L) is a susceptibility locus for systemic lupus erythematosus (SLE). Risk alleles increase TNFSF4 expression in cell…
ard.bmj.com
Apoptotic cell infusion treats ongoing collagen-induced arthritis, even in the presence of methotrexate, and is synergic with anti-TNF therapy
arthritis-research.biomedcentral.com
