Purpose of Review To review the extent of treatment success or failure with the xanthine oxidoreductase inhibitors allopurinol and…
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Response is defined as achieving uric acid level below 360 umol/L (6 mg/dL). It is more likely to be achieved with higher doses of xanthine oxidase inhibitors, and in combination with uricosuric agents.
Study results published in Rheumatology confirm the association between a mutation in the ABCG2 gene and poor response to allopurinol treatment…
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