RA ℞: B-Cell Depletion
Decreased CD4 T Cells with Rituximab Infusions Rituximab (RTX) is a monoclonal antibody directed against the CD20 antigen on B cells and when administered causes a marked depletion of CD20+…
The 9 Muses are daughters of Zeus and Mnemosyne, Greek goddesses personifying the inspiration for the sciences and the arts.
My highly opinionated news-blog draws inspiration from both the science and the art of Rheumatology.
Decreased CD4 T Cells with Rituximab Infusions Rituximab (RTX) is a monoclonal antibody directed against the CD20 antigen on B cells and when administered causes a marked depletion of CD20+…
A window of opportunity for abatacept in RA: is disease duration an independent predictor of low disease activity/remission in clinical practice? The objective of the study was to examine whether…
Key Lessons from the TNF Inhibitor Head-to-Head EXXELERATE Study The EXXELERATE study is featured prominently in Lancet this week. In some ways, this represents a landmark negative trial that rheumatologists…
No difference in efficacy for MTX as monotherapy vs. combination therapy with other csDMARDs for RA In a systematic literature review informing the 2016… healio.com Is the Jury Still Out…
Long-term Low-dose Steroids OK in Early RA Use with DMARDs and for the shortest period and the lowest possible dose medpagetoday.com "Long-term" in this study was up to 5 years,…
EULAR Releases New RA Tx Recommendations Focus is on conventional agents, biologics, and targeted synthetic drugs medpagetoday.com EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying…
Calprotectin vs Acute-Phase Reactants to Discriminate RA, PsA Activity Calprotectin discriminate disease activity in RA patients receiving tumor necrosis factor inhibitors more effectively than acute-phase reactants. rheumatologyadvisor.com Calprotectin (S100A8/A9) has…
New antibody shows potential as prognostic marker in early rheumatoid arthritis Anti-CII seropositivity may identify RA patients with acute but transient inflammation around the time of… mdedge.com The anti-fibrillar collagen…
EULAR 2016 Recommendations on Early Arthritis Combe and leading European rheumatologist have published an update to the 2007 European League Against Rheumatism (EULAR) recommendations for… rheumnow.com 2016 update of the…
Predictors of Progression in Early Inflammatory Polyarthritis A substantial, but unclear, percentage of patients presenting with new onset inflammatory polyarthritis (IP) will spontaneously remit, while others may persist and develop rheumatoid…