Debunking Psoriasis Myths: Do Systemic Steroids Used in Psoriasis Patients Cause Pustular Psoriasis?

The advent of biologic therapy for psoriasis has changed the landscape of treatments offered to…
mdedge.com

Modest Efficacy for Methotrexate in Psoriasis

Doubt remains regarding the appropriateness, efficacy and safety of methotrexate in the treatment of moderate to severe cutaneous psoriasis. Moreover, high dose,…
rheumnow.com

Subcutaneous high-dose methotrexate controls psoriasis

A little-studied route of methotrexate delivery produces rapid and sustained responses in moderate to severe psoriasis patients.
mdedge.com

Inhibition of phosphodiesterase 4 (PDE4) reduces dermal fibrosis by interfering with the release of interleukin-6 from M2 macrophages

Objectives To investigate the disease-modifying effects of phosphodiesterase 4 (PDE4) inhibition in preclinical models of systemic sclerosis (SSc). Methods We studied the effects of PDE4 inhibition in a prevention and a treatment model of bleomycin-induced skin fibrosis, in the topoisomerase mouse m…
ard.bmj.com

Valeants Brodalumab FDA Approved for Psoriasis

The drug was originally developed by Amgen…
rheumnow.com

Guselkumab Shows Superiority in Plaque Psoriasis Phase 3 Studies

Janssen announced new findings from VOYAGE 2 and NAVIGATE, two pivotal Phase 3 studies evaluating guselkumab for the treatment of moderate to…
empr.com