Diet, Lipids & CVD

Fruit, vegetable, and legume intake, and cardiovascular disease and deaths in 18 countries (PURE): a prospective cohort study

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Higher fruit, vegetable, and legume consumption was associated with a lower risk of non-cardiovascular, and total mortality. Benefits appear to be maximum for both non-cardiovascular mortality and total mortality at three to four servings per day (equivalent to 375–500 g/day).
thelancet.com

Associations of fats and carbohydrate intake with cardiovascular disease and mortality in 18 countries from five continents (PURE): a prospective cohort study

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High carbohydrate intake was associated with higher risk of total mortality, whereas total fat and individual types of fat were related to lower total mortality. Total fat and types of fat were not associated with cardiovascular disease, myocardial infarction, or cardiovascular disease mortality, wh…
thelancet.com

The cholesterol and calorie hypotheses are both dead — it is time to focus on the real culprit: insulin resistance

Illustration showing diabetes and heart disease
Emerging evidence shows that insulin resistance is…
pharmaceutical-journal.com


Low-salt diets may not be beneficial for all, study suggests: Salt reduction only important in some people with high blood pressure

A large worldwide study has found that, contrary to popular thought, low-salt diets may not be beneficial and may actually increase the risk of cardiovascular disease (CVD) and death compared to average salt consumption. The study suggests that the only people who need to worry about reducing sodium…
sciencedaily.com

Canakinumab Reduces CV Outcomes in High Risk Patients

The results of a randomized, double-blind trial have shown that canakinumab (CAN), an interleukin-1β inhibitor, given as 150 mg every 3 months, resulted in a significantly lower rate of recurrent cardiovascular events (in high-risk CV patients), independent of lipid-level lowering. (Citation source…
rheumnow.com
“Everything is autoimmune/autoinflammatory until proven otherwise.”
~ Yehuda Schonfeld