SLE Triggers

The little-understood antibody immunoglobulin E (IgE) plays a previously unknown role in systemic lupus…
www.rheumatologynetwork.com

IgE may play a previously unknown role in the triggering and pathogenesis of SLE in genetically susceptible individuals.
Often thought as an antibody mediating inflammation against allergens and parasites, it may explain the link between environmental triggers and the development of Lupus.


Lopez and colleagues from Spain have studied the gut microbiome of lupus patients and reported that lupus microbiota promoted lymphocyte activation and Th17…
rheumnow.com

If this idea that dysbiosis may be driving SLE inflammation, then we are sleeping with the enemy without knowing it. It also means that tweaking the microbiome with antibiotics, probiotics and probiotics may help in disease control.

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